Basic Continous Training Course 16th Symposium

Session 1

HIV and the central nervous system

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Scott Letendre, M.D.

University of California. San Diego, USA

Scott Letendre, M.D., is Professor of Medicine in Residence in the Division of Infectious Diseases at the University of California, San Diego (UCSD). He graduated from Georgetown University School of Medicine and, following his residency in internal medicine at the Naval Medical Center in San Diego, he completed fellowships in Infectious Disease Medicine at Duke University and in Neurologic HIV Research at UCSD. At UCSD, Dr. Letendre performs translational, patient-oriented research of the central nervous system complications of chronic infections, including HIV, HCV, and CMV. As part of a multidisciplinary research team, he conducts treatment trials of neurocognitively impaired individuals and analyzes their response to therapy as well as studies of the pharmacokinetics of antiretrovirals, the effect of comorbidities, and biomarker correlates of disease. Dr. Letendre is also an investigator in the UCSD unit of the AIDS Clinical Trials Group.

He participates in several international research projects, including projects based in China, India, Zambia, and Romania. Dr

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Andrea Calcagno, M.D., DTM&H

University of Torino, Italy

He is temporary Assistant Professor at the University of Torino (Department of Medical Sciences, Infectious Diseases). Infectious Diseases Specialist (University of Torino, Italy); Diploma in Tropical Medicine and Hygiene (Mahidol University, Bangkok, Thailand). He is member of the Panel of the Italian Guidelines on the Use of Antiretrovirals and Management of patients living with HIV.

He has experience as a Clinicians in Infectious Diseases and Tropical Medicine (Sudan, Thailand, Burundi); several phase II, III and IV studies in antiretroviral treatment trials.

His main field of interest is the clinical pharmacology and pharmacogenetics of anti-infective agents (antiretroviral, antibiotic, antifungals) and the central nervous system complication of HIV-infection.

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